Cyclohexanone Oxime → Enantholactam

HRID 1805738Notes

Reaction equation

HRID 1805738 reaction equation
[C:1]1(=[N:7][OH:8])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[C:9]1(=[O:16])[NH:15][CH2:14][CH2:13][CH2:12][CH2:11][CH2:10]1.[C:17]1(=NO)CCCCC[CH2:18]1>>[C:9]1(=[O:16])[NH:15][CH2:14][CH2:13][CH2:12][CH2:11][CH2:10][CH2:1]1.[C:1]1(=[N:7][OH:8])[CH2:18][CH2:17][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1

Participants

5

Reactant 3

HCID 7517Cyclohexanone OximeHCID 7768CaprolactamHCID 137457Cycloheptanone Oxime

Product 2

HCID 12657EnantholactamHCID 136841Cyclooctanone, oxime

Procedure

For example, cyclohexanone oxime gives ε-caprolactam, cycloheptanone oxime gives 7-heptane lactam, cyclooctanone oxime gives 8-octane lactam, and cyclododecanone oxime gives laurolactam

Sources & evidence

ORD record
ord-c3ec293e8ca44fee9d97da936a332495
Source dataset
uspto-grants-2013_01
Patent number
US08354527B2

Reaction notes

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