HCID 13931105, compound → HCID 86623296, compound

HRID 1805767Notes

Reaction equation

HRID 1805767 reaction equation
[C:1]([CH2:3][CH2:4][N:5]([CH2:18][CH2:19][C:20]#[N:21])[CH2:6][CH:7]([N:9]([CH2:14][CH2:15][C:16]#[N:17])[CH2:10][CH2:11][C:12]#[N:13])[CH3:8])#[N:2].[H][H]>O1CCOCC1>[NH2:2][CH2:1][CH2:3][CH2:4][N:5]([CH2:18][CH2:19][CH2:20][NH2:21])[CH2:6][CH:7]([N:9]([CH2:14][CH2:15][CH2:16][NH2:17])[CH2:10][CH2:11][CH2:12][NH2:13])[CH3:8]

Participants

4

Reactant 2

HCID 13931105HCID 13931105, compoundHCID 178418361HCID 178418361, compound

Product 1

HCID 86623296HCID 86623296, compoundYield 96.9%

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent

Procedure

20.05 g of N,N,N′,N′-tetrakis(2-cyanoethyl)-1,2-diaminopropane, 2.01 g of Raney Co and 100 mL of 1,4-dioxane were charged in an autoclave and a hydrogenation reaction was carried out at an initial hydrogen pressure of 9.0 MPa at 160° C. for 3 hours. After the catalyst was removed by filtration, the obtained filtrate was concentrated to dryness to give 20.52 g of the title compound as a white solid.

Workup

  1. customa hydrogenation reaction
  2. customAfter the catalyst was removed by filtration
  3. concentrationthe obtained filtrate was concentrated to dryness

Sources & evidence

ORD record
ord-3ee56a902cdd4975a64297e183a0a119
Source dataset
uspto-grants-2013_01
Patent number
US08354529B2

Reaction notes

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