HCID 86623299, compound → HCID 66776913, compound

HRID 1805769Notes

Reaction equation

HRID 1805769 reaction equation
[C:1]([CH2:3][CH2:4][N:5]([CH2:10][CH:11]1[CH2:16][CH2:15][CH2:14][CH:13]([CH2:17][N:18]([CH2:23][CH2:24][C:25]#[N:26])[CH2:19][CH2:20][C:21]#[N:22])[CH2:12]1)[CH2:6][CH2:7][C:8]#[N:9])#[N:2].[H][H]>O1CCOCC1>[NH2:22][CH2:21][CH2:20][CH2:19][N:18]([CH2:17][CH:13]1[CH2:14][CH2:15][CH2:16][CH:11]([CH2:10][N:5]([CH2:4][CH2:3][CH2:1][NH2:2])[CH2:6][CH2:7][CH2:8][NH2:9])[CH2:12]1)[CH2:23][CH2:24][CH2:25][NH2:26]

Participants

4

Reactant 2

HCID 86623299HCID 86623299, compoundHCID 178418361HCID 178418361, compound

Product 1

HCID 66776913HCID 66776913, compoundYield 97.6%

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent

Procedure

5.00 g of N,N,N′,N′-tetrakis(2-cyanoethyl)-1,3-bis(aminomethyl)cyclohexane, 0.50 g of Raney Co and 50 mL of 1,4-dioxane were charged in an autoclave and a hydrogenation reaction was carried out at an initial hydrogen pressure of 8.0 MPa at 180° C. for 2 hours. After the catalyst was removed by filtration, the obtained filtrate was concentrated to dryness to give 5.10 g of the title compound as a pale red oil.

Workup

  1. customa hydrogenation reaction
  2. customAfter the catalyst was removed by filtration
  3. concentrationthe obtained filtrate was concentrated to dryness

Sources & evidence

ORD record
ord-7d286a12235344e485df2f9ba53d2575
Source dataset
uspto-grants-2013_01
Patent number
US08354529B2

Reaction notes

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