HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1805896Generated: October 27, 2026
Methanesulfonic Acid → Dabigatran Etexilate Mesylate
https://huagongshe.com/reaction/1805896
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Methanesulfonic Acid | HCID 6395 | — |
| Reactant | Dabigatran Etexilate | HCID 135565674 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | Dabigatran Etexilate Mesylate | HCID 135566083 | — |
Reaction Steps
100 g (0.16 mol) of the compound (6B) are dissolved in 890 ml acetone with heating and combined with a solution of 15 g (0.16 mol) methanesulphonic acid in 200 ml acetone. The solution is filtered and after the addition of 77 ml acetone cooled to approx. 20° C. The precipitated product is isolated and washed with acetone.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08354543B2 |
|---|
| Source dataset | uspto-grants-2013_01 |
|---|
| ORD ID | ord-1900d15b50ae4817a9c5a5697cc7d246 |
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| Source note | uspto-grants-2013_01 |
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