HCID 67419312, compound → HCID 67375568, compound

Participants

Reaction Conditions

Reaction Steps

A suspension of 10% palladium on carbon (172 mg, 0.162 mmol) in a solution of 2-phenyl-5[2-(tetrahydro-2H-pyran-2-yloxy)ethoxy]-1,3-dioxane (498.9 mg, 1.618 mmol) in EtOAc (32.4 mL) was stirred under H2 at 25° C. for 3 days. The reaction mixture was filtered through a plug of Celite and the filtrate was concentrated in vacuo to afford 2-[2-(tetrahydro-2H-pyran-2-yloxy)ethoxy]propane-1,3-diol. LCMS calc.=243.12; found=243.22 (M+Na)+.

Provenance & Evidence