HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 68771066, compound → HCID 42646799, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 68771066 | HCID 68771066 | — |
| Catalyst | Palladium hydroxide | HCID 9942167 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 42646799 | HCID 42646799 | — |
Reaction Steps
To 1-Benzyl-3-[(2-benzylpyrrolidin-1-yl)carbonyl]-4-(2-methylphenyl)pyrrolidine (0.1 g, 0.228 mmol) in MeOH (10 ml) was added Pearlman's Catalyst (0.05 g, 0.071 mmol) and hydrogenated with a balloon for 2 hours. Filter through celite, concentrate, and purify on reverse phase HPLC. LRMS (M+H)=349.13
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08354545B2 |
| Source dataset | uspto-grants-2013_01 |
| ORD ID | ord-58cb196dd896466e9169f06e2dd44071 |
| Source note | uspto-grants-2013_01 |