HuagongsheHuagongshe Chemistry Print Report · For research reference only
tert-Butyl 4-(2-Bromoacetyl)piperidine-1-carboxylate → Tert-butyl 4-(2-(5-bromo-3-phenoxypyridin-2-ylamino)thiazol-4-yl)piperidine-1-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | tert-Butyl 4-(2-Bromoacetyl)piperidine-1-carboxylate | HCID 18187487 | — |
| Reactant | 1-(5-Bromo-3-phenoxypyridin-2-yl)thiourea | HCID 86631481 | — |
| Product | Tert-butyl 4-(2-(5-bromo-3-phenoxypyridin-2-ylamino)thiazol-4-yl)piperidine-1-carboxylate | HCID 86631480 | — |
Reaction Steps
Following the procedure in Example 7, step E using 1-(5-bromo-3-phenoxypyridin-2-yl)thiourea and tert-butyl 4-(2-bromoacetyl)piperidine-1-carboxylate provided tert-butyl 4-(2-(5-bromo-3-phenoxypyridin-2-ylamino)thiazol-4-yl)piperidine-1-carboxylate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08354540B2 |
| Source dataset | uspto-grants-2013_01 |
| ORD ID | ord-f559416c957e490ebaafc41c35b4db2c |
| Source note | uspto-grants-2013_01 |