HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Bromo-4-phenylbutan-2-one → N-(5-Bromo-3-phenoxypyridin-2-yl)-4-phenethylthiazol-2-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Bromo-4-phenylbutan-2-one | HCID 12608027 | — |
| Reactant | 1-(5-Bromo-3-phenoxypyridin-2-yl)thiourea | HCID 86631481 | — |
| Product | N-(5-Bromo-3-phenoxypyridin-2-yl)-4-phenethylthiazol-2-amine | HCID 57742623 | — |
Reaction Steps
Prepared according to the method of Example 7 Step E from 1-(5-bromo-3-phenoxypyridin-2-yl)thiourea and 1-bromo-4-phenylbutan-2-one. 1H NMR (d6-DMSO) δ 8.26 (m, 1H), 7.45 (m, 3H), 7.31-7.11 (m, 8H), 6.74 (s, 1H), 2.92 (m, 4H). Mass spectrum (apci) m/z=452.3 (M+H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08354540B2 |
| Source dataset | uspto-grants-2013_01 |
| ORD ID | ord-eee20fc777fc4505a6cafb08f5912148 |
| Source note | uspto-grants-2013_01 |