HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzoyl isothiocyanate → 1-Benzoyl-3-(5-bromo-3-(4-fluorophenoxy)pyridin-2-yl)thiourea
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzoyl isothiocyanate | HCID 68284 | — |
| Reactant | 5-Bromo-3-(4-fluorophenoxy)pyridin-2-amine | HCID 66994490 | — |
| Product | 1-Benzoyl-3-(5-bromo-3-(4-fluorophenoxy)pyridin-2-yl)thiourea | HCID 86631484 | 91.2% |
Reaction Steps
Following the procedure in Example 7, Step C, 5-bromo-3-(4-fluorophenoxy)pyridin-2-amine (800 mg, 2.83 mmol) and benzoyl isothiocyanate (0.457 mL, 3.39 mmol) afforded 1-benzoyl-3-(5-bromo-3-(4-fluorophenoxy)pyridin-2-yl)thiourea (1150 mg, 91.2% yield).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08354540B2 |
| Source dataset | uspto-grants-2013_01 |
| ORD ID | ord-804192e54ed44876ae62e6e44f644b10 |
| Source note | uspto-grants-2013_01 |