Sodium;3-oxidodioxaborirane;tetrahydrate → (1,1-Dioxo-hexahydro-1lambda6-thiopyran-4-yl)-pyridin-2-yl-methanol

Participants

Reaction Steps

Placed pyridin-2-yl(tetrahydro-2H-thiopyran-4-yl)methanol (1.560 g, 7.453 mmol) in glacial acetic acid (2 mL). Sodium perborate tetrahydrate (2.293 g, 14.91 mmol) was added and stirred for 18 hours. The reaction was partitioned between saturated sodium bisulfite and CH2Cl2. The solids were filtered off, washed with water and dried to afford the title compound (1.233 g, 68.56% yield)

Provenance & Evidence