HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methylamine → HCID 16036912, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methylamine | HCID 6329 | — |
| Reactant | Sodium borohydride | HCID 4311764 | — |
| Reactant | 3-[1-(ethylsulfonyl)-4-piperidinyl]-5-(3-formylphenyl)-1H-indole-7-carboxamide | HCID 57732804 | — |
| Product | HCID 16036912 | HCID 16036912 | 83.1% |
Reaction Steps
Following the general procedure of example 24, 3-[1-(ethylsulfonyl)-4-piperidinyl]-5-(3-formylphenyl)-1H-indole-7-carboxamide (20 mg, 0.045 mmol), methylamine (130 uL, 0.27 mmol) and NaBH4 (10 mg, 0.27 mmol) were reacted to give title compound (17.0 mg, 83%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08354406B2 |
| Source dataset | uspto-grants-2013_01 |
| ORD ID | ord-bb8f36551fc14a92bd7f3f90bf471751 |
| Source note | uspto-grants-2013_01 |