HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetyl chloride → HCID 57732675, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetyl chloride | HCID 6367 | — |
| Reactant | HCID 66722703 | HCID 66722703 | — |
| Product | HCID 57732675 | HCID 57732675 | 28% |
Reaction Steps
The title compound was prepared according to the general procedure of 5-{4-[(acetylamino)methyl]phenyl}-3-[1-(ethylsulfonyl)-4-piperidinyl]-1H-indole-7-carboxamide substituting cyclopropanecarbonyl chloride (14 μL, 1.37 mmol) for acetyl chloride. Compound was purified by Gilson Preparatory HPLC to afford 19.1 mg of the title compound (28%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08354406B2 |
| Source dataset | uspto-grants-2013_01 |
| ORD ID | ord-cd25fdc337f2499484300c3052034a46 |
| Source note | uspto-grants-2013_01 |