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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1806422Generated: November 2, 2026

Dimethylamine → HCID 66723549, compound

https://huagongshe.com/reaction/1806422

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylamineHCID 674—
ReactantIsopropylamineHCID 6363—
ReactantHCID 66723061HCID 66723061—
ProductHCID 66723549HCID 6672354924%

Reaction Steps

The title compound was prepared according to the general procedure of 5-[3-[(dimethylamino)methyl]-4-(methyloxy)phenyl]-3-[1-(ethylsulfonyl)-4-piperidinyl]-1H-indole-7-carboxamide trifluoroacetate, substituting 2-propanamine (15 μL, 0.214 mmol) for the dimethylamine to afford 16 mg of the title compound (24%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08354406B2
Source datasetuspto-grants-2013_01
ORD IDord-3c124097e1a049d68bd7ae043445f109
Source noteuspto-grants-2013_01