HuagongsheHuagongshe Chemistry Print Report · For research reference only
(R)-(-)-2-Amino-1-propanol → HCID 66722903, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (R)-(-)-2-Amino-1-propanol | HCID 80308 | — |
| Reactant | HCID 66722888 | HCID 66722888 | — |
| Product | HCID 66722903 | HCID 66722903 | 14.7% |
Reaction Steps
The title compound was prepared according to the general procedure of 3-[1-(ethylsulfonyl)-4-piperidinyl]-5-(5-{[[(1S)-2-hydroxy-1-methylethyl](methyl)amino]methyl}-3-thienyl)-1H-indole-7-carboxamide trifluoroacetate (salt), substituting (cyclopropylmethyl)amine (1.20 mmol) for (2R)-2-amino-1-propanol to afford 6.2 mg of the title compound (14.7%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08354406B2 |
| Source dataset | uspto-grants-2013_01 |
| ORD ID | ord-604b9af3fec94d6f9aa73d417d00e8a9 |
| Source note | uspto-grants-2013_01 |