HuagongsheHuagongshe Chemistry Print Report · For research reference only
Glycine tert-butyl ester → HCID 178451247, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Glycine tert-butyl ester | HCID 151417 | — |
| Reactant | 2-Cyclohexylacetaldehyde | HCID 316627 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 178451247 | HCID 178451247 | 96.1% |
Reaction Steps
In a manner similar to the method described in Example 1a, glycine tert-butyl ester (1.3 g, 10 mmol) was reacted with 2-cyclohexylacetaldehyde (Betapharma) (1.3 g, 10 mmol) in CH2Cl2 at room temperature for 5 h to give [2-cyclohexyl-eth-(E)-ylideneamino]-acetic acid tert-butyl ester as a colorless oil (2.3 g, 96%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08354444B2 |
| Source dataset | uspto-grants-2013_01 |
| ORD ID | ord-361a89e856f843218d8f723566afea90 |
| Source note | uspto-grants-2013_01 |