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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1807143Generated: November 1, 2026

HCID 45139216, compound → HCID 45139217, compound

https://huagongshe.com/reaction/1807143

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 45139216HCID 45139216—
SolventTrifluoroacetic acid methylene chlorideHCID 21863450—
ProductHCID 45139217HCID 45139217—

Reaction Steps

rac 4-{[(2R,3S,4R,5S)-3-(3-Chloro-2-fluoro-phenyl)-4-(4-chloro-2-fluoro-phenyl)-4-cyano-5-(2,2-dimethyl-propyl)-pyrrolidine-2-carbonyl]-amino}-benzoic acid t-butyl ester (35 mg, 0.031 mmol) was treated with 30% TFA/methylene chloride (10 mL) overnight. Removal of solvent and freeze drying of the residue give a white powder. 31 mg.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08354444B2
Source datasetuspto-grants-2013_01
ORD IDord-cc5bb3a602bf42a68525d339de3faaf2
Source noteuspto-grants-2013_01