Dabco → HCID 90143829, compound

Participants

Reaction Steps

A solution of 3-difluoromethyl-1-methyl-1H-pyrazole-4-carbonyl chloride (24 mg; 0.12 mmol) in acetonitrile (1 ml) was added dropwise to a stirred mixture of N-{1-[2-(2,4,6-trichlorophenyl)-cyclopropyl]-ethyl}-O-methyl-hydroxylamine (24 mg; 0.08 mmol), prepared as described in example P16 and DABCO (14 mg; 0.12 mmol) in acetonitrile (1 ml) at ambient temperature. The reaction mixture was stirred for 2 hours at ambient temperature. The solvent was removed in vacuo and the residue was purified by flash chromatography over silica gel (4 g) (eluent: n-hexane/ethyl acetate 1:2).

Provenance & Evidence