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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1807414Generated: October 31, 2026

Morpholine → Retosiban

https://huagongshe.com/reaction/1807414

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMorpholineHCID 8083—
Reactant{(3R,6R)-3-(2,3-dihydro-1H-inden-2-yl)-6-[(1R)-1-methylpropyl]-2,5-dioxo-1-piperazinyl}(2-methyl-1,3-oxazol-4-yl)acetic acidHCID 66628767—
ProductRetosibanHCID 11340891—

Reaction Steps

Similarly was prepared from intermediate 4 and morpholine

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08357685B2
Source datasetuspto-grants-2013_01
ORD IDord-18ae28d8f998435c97ac567c9aa2f5e0
Source noteuspto-grants-2013_01