HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Azide → 1-(azidomethyl)-4-chlorobenzene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Azide | HCID 33557 | — |
| Reactant | 1-(Bromomethyl)-4-chlorobenzene | HCID 69329 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | 1-(azidomethyl)-4-chlorobenzene | HCID 11171194 | — |
Reaction Steps
A solution of 4-chlorobenzyl bromide in acetone was treated with NaN3 and refluxed for 3 hours. The reactions was concentrated by 50% and diluted with saturated sodium chloride solution. The reaction was then extracted with Et2O, washed with brine, dried (Na2SO4) and concentrated to give 1-(azidomethyl)-4-chlorobenzene.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08357699B2 |
| Source dataset | uspto-grants-2013_01 |
| ORD ID | ord-916cf4eb657048828066668f4c319eef |
| Source note | uspto-grants-2013_01 |