2-Propanol, 1-amino-2-methyl- → HCID 49800452, compound

Participants

Reaction Steps

As described for example 9, 6-(3-butyl-5-methyl-isoxazol-4-ylmethoxy)-nicotinic acid methyl ester (150 mg, 0.49 mmol) was converted, using 1-amino-2-methyl-propan-2-ol instead of rac-2-amino-1-propanol, to the title compound (10 mg, 6%) which was obtained as a colourless oil after purification by chromatography (silica, 0 to 5% methanol in dichloromethane). MS: m/e=362.3 [M+H]+.

Provenance & Evidence