Serinol → HCID 49800454, compound

Participants

Reaction Steps

As described for example 9, 6-(3-butyl-5-methyl-isoxazol-4-ylmethoxy)-nicotinic acid methyl ester (150 mg, 0.49 mmol) was converted, using 2-amino-1,3-propanediol instead of rac-2-amino-1-propanol, to the title compound (53 mg, 30%) which was obtained as a white solid after purification by chromatography (silica, 0 to 8% methanol in dichloromethane). MS: m/e=364.3 [M+H]+.

Provenance & Evidence