HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-(3-Butyl-5-methyl-isoxazol-4-ylmethoxy)-nicotinic acid methyl ester → HCID 49801029, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-(3-Butyl-5-methyl-isoxazol-4-ylmethoxy)-nicotinic acid methyl ester | HCID 66599158 | — |
| Reactant | HCID 66643593 | HCID 66643593 | — |
| Product | HCID 49801029 | HCID 49801029 | 62% |
Reaction Steps
As described for example 5d, 6-(3-cyclopentyl-5-methyl-isoxazol-4-ylmethoxy)-nicotinic acid methyl ester (230 mg, 0.73 mmol) was converted, instead of 6-(3-butyl-5-methyl-isoxazol-4-ylmethoxy)-nicotinic acid methyl ester, to the title compound (155 mg, 62%) which was obtained as a white solid after purification by chromatography (silica, 0 to 80% ethyl acetate in heptane). MS: m/e=344.0 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08357703B2 |
| Source dataset | uspto-grants-2013_01 |
| ORD ID | ord-5944a93b3d444ab9b73c94971180e50b |
| Source note | uspto-grants-2013_01 |