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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1807521Generated: October 30, 2026

HCID 66643566, compound → HCID 49801306, compound

https://huagongshe.com/reaction/1807521

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 66643566HCID 66643566—
ReactantHCID 66643593HCID 66643593—
ProductHCID 49801306HCID 498013064%

Reaction Steps

As described for example 30d, 6-(3-cyclohexyl-5-methyl-isoxazol-4-ylmethoxy)-nicotinic acid methyl ester (708 mg, 1.5 mmol), instead of 6-(3-cyclopentyl-5-methyl-isoxazol-4-ylmethoxy)-nicotinic acid methyl ester, was converted to the title compound (19 mg, 4%) which was obtained as a white solid after purification by chromatography (silica, 0 to 5% methanol in dichloromethane) and trituration with diisopropyl ether. MS: m/e=358.5 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08357703B2
Source datasetuspto-grants-2013_01
ORD IDord-3d253d83a15f4f61af417e4effea9333
Source noteuspto-grants-2013_01