HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 66643566, compound → HCID 49801306, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 66643566 | HCID 66643566 | — |
| Reactant | HCID 66643593 | HCID 66643593 | — |
| Product | HCID 49801306 | HCID 49801306 | 4% |
Reaction Steps
As described for example 30d, 6-(3-cyclohexyl-5-methyl-isoxazol-4-ylmethoxy)-nicotinic acid methyl ester (708 mg, 1.5 mmol), instead of 6-(3-cyclopentyl-5-methyl-isoxazol-4-ylmethoxy)-nicotinic acid methyl ester, was converted to the title compound (19 mg, 4%) which was obtained as a white solid after purification by chromatography (silica, 0 to 5% methanol in dichloromethane) and trituration with diisopropyl ether. MS: m/e=358.5 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08357703B2 |
| Source dataset | uspto-grants-2013_01 |
| ORD ID | ord-3d253d83a15f4f61af417e4effea9333 |
| Source note | uspto-grants-2013_01 |