Ethanolamine → HCID 49801309, compound

Participants

Reaction Steps

As described for example 31e, 6-(3-cyclohexyl-5-methyl-isoxazol-4-ylmethoxy)-nicotinic acid methyl ester (708 mg, 1.5 mmol) was converted, using ethanolamine instead of isopropylamine, to the title compound (55 mg, 10%) which was obtained as a light yellow oil after purification by chromatography (silica, 0 to 5% methanol in dichloromethane). MS: m/e=360.4 [M+H]+.

Provenance & Evidence