Dichloromethane → HCID 58317839, compound

Participants

Reaction Steps

To a solution of intermediate 29 (0.675 g, 1 mmol), in dichloromethane 50 mL tri-fluoro-acetic acid (2.86 g, 20 mmol) was added. The resulting mixture was stirred at room temperature for 12 hours. The solvent was removed then the residue was purified by column chromatography using dichloromethane/methanol to yield 0.55 g (95%) of methyl [2-(6-{[(4-aminobutyl)(methyl)sulfamoyl]carbamoyl}-3-cyclohexyl-1-methyl-1H-indol-2-yl)phenoxy]acetate 30: m/z=585 (M+H)+.

Provenance & Evidence