HuagongsheHuagongshe Chemistry Print Report · For research reference only
Isoquinoline, 1-chloro- → 2-(RS)-(Isoquinolin-1-ylaminomethyl)-piperidine-1-carboxylic acid tert butyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Isoquinoline, 1-chloro- | HCID 140539 | — |
| Reactant | tert-Butyl 2-(aminomethyl)piperidine-1-carboxylate | HCID 2756482 | — |
| Product | 2-(RS)-(Isoquinolin-1-ylaminomethyl)-piperidine-1-carboxylic acid tert butyl ester | HCID 86593669 | — |
Reaction Steps
The title compound (0.76 g) was prepared from (RS) 2-aminomethyl-piperidine-1-carboxylic acid tert butyl ester (1.6 ml) and 1-chloroisoquinoline (0.8 g) according to the method used for the preparation of the compound of D8.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07741329B2 |
| Source dataset | uspto-grants-2010_06 |
| ORD ID | ord-b00d72bdee644a93bd9c454a819cb045 |
| Source note | uspto-grants-2010_06 |