N-Methylbutylamine → HCID 67427968, compound

Participants

Reaction Steps

This was synthesized by using (S)-4-(6-(4-chlorophenyl)-5,6-dihydrobenzo[h]quinazolin-2-ylamino)phenethyl methanesulfonate, N-methylbutan-1-amine and triethylamine as described in general procedure 2 to give a yellow solid. M.p.=75-77° C. 1H NMR 400 MHz (DMSO-d6) δ 9.90 (s, br, 1H), 9.59 (s, 1H), 8.30 (m, 2H), 7.79 (d, J=8.4 Hz, 2H), 7.50-7.44 (m, 2H), 7.31 (m, 2H), 7.22 (d, J=8.8 Hz, 2H), 7.10 (m, 4H), 4.42 (t, J=5.6 Hz, 1H), 3.28-2.86 (m, 8H), 2.78 (d, J=5.2 Hz, 3H), 1.67-1.59 (m, 2H), 1.33-1.27 (m, 2H), 0.90 (t, J=7.2 Hz, 3H). LCMS m/e 497 (M+H).

Provenance & Evidence