N-Methylcyclohexylamine → HCID 67541432, compound

Participants

Reaction Steps

This was synthesized by using (S)-4-(6-(4-chlorophenyl)-5,6-dihydrobenzo[h]quinazolin-2-ylamino)phenethyl methanesulfonate, N-methylcyclohexanamine and triethylamine as described in general procedure 2 to give a yellow solid. M.p.=159-162° C. 1H NMR 400 MHz (DMSO-d6) δ 9.96 (s, br, 1H), 9.59 (s, 1H), 8.28 (m, 2H), 7.78 (d, J=8.4 Hz, 2H), 7.49-7.43 (m, 2H), 7.30 (m, 2H), 7.23 (d, J=8.8 Hz, 4H), 7.09 (m, 4H), 4.41 (t, J=6.0 Hz, 1H), 3.29-2.94 (m, 8H), 2.72 (d, J=5.2 Hz, 3H), 2.03-1.10 (m, 10H). LCMS m/e 523 (M+H).

Provenance & Evidence