HCID 67426541, compound → HCID 59490004, compound

HRID 1808083Notes

Reaction equation

HRID 1808083 reaction equation
CN(/[CH:4]=[C:5]1\[C:6](=O)[C:7]2[C:12]([C@H:13]([C:15]3[CH:20]=[CH:19][CH:18]=[CH:17][C:16]=3[F:21])[CH2:14]\1)=[CH:11][CH:10]=[CH:9][CH:8]=2)C.[N:23]1([C:29]2[CH:34]=[CH:33][C:32]([NH:35][C:36]([NH2:38])=[NH:37])=[CH:31][CH:30]=2)[CH2:28][CH2:27][NH:26][CH2:25][CH2:24]1>>[F:21][C:16]1[CH:17]=[CH:18][CH:19]=[CH:20][C:15]=1[C@H:13]1[C:12]2[CH:11]=[CH:10][CH:9]=[CH:8][C:7]=2[C:6]2[N:38]=[C:36]([NH:35][C:32]3[CH:31]=[CH:30][C:29]([N:23]4[CH2:28][CH2:27][NH:26][CH2:25][CH2:24]4)=[CH:34][CH:33]=3)[N:37]=[CH:4][C:5]=2[CH2:14]1

Participants

3

Reactant 2

HCID 67426541HCID 67426541, compoundHCID 178512564HCID 178512564, compound

Product 1

HCID 59490004HCID 59490004, compound

Procedure

This was synthesized by using (R,Z)-2-((dimethylamino)methylene)-4-(2-fluorophenyl)-3,4-dihydronaphthalen-1(2H)-one and 1-(4-(piperazin-1-yl)phenyl)guanidine as described in general procedure 1. LCMS m/e 452 (M+H).

Workup

  1. customThis was synthesized

Sources & evidence

ORD record
ord-5cea66de850a40dc9ac8d574382e6a50
Source dataset
uspto-grants-2013_01
Patent number
US08357694B2

Reaction notes

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