HuagongsheHuagongshe Chemistry Print Report · For research reference only
Chlorotrimethylsilane → HCID 68787557, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Chlorotrimethylsilane | HCID 6397 | — |
| Reactant | HCID 44241901 | HCID 44241901 | — |
| Solvent | Methyl Ethyl Ketone | HCID 6569 | — |
| Product | HCID 68787557 | HCID 68787557 | — |
Reaction Steps
(S)-2-(4-(dimethylamino)-4-phenylcyclohexylamino)-3-(1H-indol-3-yl)-N,N-dimethylpropanamide (240 mg, 0.55 mmol, non-polar diastereomer from step 3) was dissolved in ethyl methyl ketone (10 ml) and mixed with Me3SiCl (0.18 ml, 1.39 mmol). The white crystalline solid was aspirated after 1 h.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08357705B2 |
| Source dataset | uspto-grants-2013_01 |
| ORD ID | ord-3765d34dfe6e4524b3a326c0e09308b8 |
| Source note | uspto-grants-2013_01 |