HCID 86634823, compound → HCID 68921165, compound

Participants

Reaction Conditions

Reaction Steps

A solution of (R)-tert-butyl-3-(1H-indol-3-yl)-1-oxo-1-(prop-2-ynylamino)propan-2-yl carbamate (2.20 g, 6.44 mmol) in acetonitrile (25 mL) was mixed with gold(III) chloride (190 mg, 0.63 mmol) at room temperature and stirred for 18 h at 50° C. The solvent was removed in a vacuum and the residue was purified by flash chromatography (60 g, 15×4 cm) with ethyl acetate/cyclohexane (1:1).

Provenance & Evidence