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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 1808155생성일: 2026년 10월 25일

3-Fluoro-4-(trifluoromethyl)benzylamine → N-[3-fluoro-4-(trifluoromethyl)benzyl]-4-[(1,2,4-thiadiazol-5-ylamino)sulfonyl]benzamide

https://huagongshe.com/reaction/1808155

반응식

참여 물질

역할이름HCID투입량
반응물3-Fluoro-4-(trifluoromethyl)benzylamineHCID 2737567—
반응물4-[(1,2,4-Thiadiazol-5-ylamino)sulfonyl]benzoic acidHCID 57732214—
생성물N-[3-fluoro-4-(trifluoromethyl)benzyl]-4-[(1,2,4-thiadiazol-5-ylamino)sulfonyl]benzamideHCID 57732202—

반응 단계

The title compound was prepared from 4-[(1,2,4-thiadiazol-5-ylamino)sulfonyl]benzoic acid (Preparation 29) and 3-fluoro-4-(trifluoromethyl)benzylamine following the procedure described in Example 309. The reaction mixture was extracted from saturated sodium hydrogen carbonate into DCM and the crude product purified by preparative HPLC.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US08357711B2
출처 데이터셋uspto-grants-2013_01
ORD IDord-371732d7ff51469b9d371ce392739c0b
출처 메모uspto-grants-2013_01