HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(Trifluoromethyl)benzylamine → 4-{[(5-Chloro-1,3-thiazol-2-yl)amino]sulfonyl}-2-cyano-N-[4-(trifluoromethyl)benzyl]benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(Trifluoromethyl)benzylamine | HCID 76804 | — |
| Reactant | 4-{[(5-Chloro-1,3-thiazol-2-yl)amino]sulfonyl}-2-cyanobenzoic acid | HCID 86630781 | — |
| Product | 4-{[(5-Chloro-1,3-thiazol-2-yl)amino]sulfonyl}-2-cyano-N-[4-(trifluoromethyl)benzyl]benzamide | HCID 57731989 | — |
Reaction Steps
The title compound was prepared from 4-(trifluoromethyl)benzylamine and 4-{[(5-chloro-1,3-thiazol-2-yl)amino]sulfonyl}-2-cyanobenzoic acid of Preparation 22, following Method O described for Example 344. The reaction mixture was stirred at room temperature for 18 hours.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08357711B2 |
| Source dataset | uspto-grants-2013_01 |
| ORD ID | ord-4c46a5aa359d4048b89e7fa9eb622a4c |
| Source note | uspto-grants-2013_01 |