HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
3-Fluoro-4-(trifluoromethyl)benzylamine → 4-{[(5-Chloro-1,3-thiazol-2-yl)amino]sulfonyl}-2-cyano-N-[3-fluoro-4-(trifluoromethyl)benzyl]benzamide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 3-Fluoro-4-(trifluoromethyl)benzylamine | HCID 2737567 | — |
| Edukt | 4-{[(5-Chloro-1,3-thiazol-2-yl)amino]sulfonyl}-2-cyanobenzoic acid | HCID 86630781 | — |
| Produkt | 4-{[(5-Chloro-1,3-thiazol-2-yl)amino]sulfonyl}-2-cyano-N-[3-fluoro-4-(trifluoromethyl)benzyl]benzamide | HCID 57732196 | — |
Reaktionsschritte
The title compound was prepared from 3-fluoro-4-(trifluoromethyl)benzylamine and 4-{[(5-chloro-1,3-thiazol-2-yl)amino]sulfonyl}-2-cyanobenzoic acid of Preparation 22, following Method O described for Example 344. The reaction mixture was stirred at room temperature for 18 hours.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08357711B2 |
| Quelldatensatz | uspto-grants-2013_01 |
| ORD ID | ord-0421cfd3fdb94f7581d5516e348cb354 |
| Quellennotiz | uspto-grants-2013_01 |