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HRID1808194

反应详情

EQUATION

反应方程式

HRID 1808194 的结构方程式

REACTANTS

反应物

3
结构：O=S(Cl)Cl
HCID24386

Thionyl chloride

Cl2OS

结构：NCc1ccc(C(F)(F)F)c(Cl)c1
HCID23512744

1-[3-Chloro-4-(trifluoromethyl)phenyl]methanamine

C8H7ClF3N

结构：O=C([O-])c1ccc(S(=O)(=O)O)cc1.[K+]
HCID23670833

Benzoic acid, 4-sulfo-, monopotassium salt

C7H5KO5S

PRODUCTS

生成物

1
结构：O=C(NCc1ccc(C(F)(F)F)c(Cl)c1)c1ccc(S(=O)(=O)Cl)cc1
HCID57731928

未命名化合物

收率 45%

PROCEDURE

实验过程

The title compound was prepared from 4-sulphobenzoic acid monopotassium salt and 3-chloro-4-(trifluoromethyl)benzylamine in 45% yield following the procedure described in Preparation 1. The thionyl chloride solution was heated at reflux for 3 hours.

WORKUP

后处理

  1. customdescribed in Preparation 1
  2. temperatureat reflux for 3 hours