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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1808228Generated: October 31, 2026

5-Bromopyrimidine → 5-(Piperidin-3-ylmethyl)pyrimidine

https://huagongshe.com/reaction/1808228

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-BromopyrimidineHCID 78344—
ReactantTert-butyl 3-(iodomethyl)piperidine-1-carboxylateHCID 20716152—
Reactant2-(Piperidin-3-ylmethyl)pyrimidineHCID 57731945—
Product5-(Piperidin-3-ylmethyl)pyrimidineHCID 57732222—

Reaction Steps

Made in an analogue manner to 2-(piperidin-3-ylmethyl)pyrimidine using 5-bromopyrimidine with tert-butyl 3-(iodomethyl)piperidine-1-carboxylate.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08357711B2
Source datasetuspto-grants-2013_01
ORD IDord-12a1c12ea66847f6a36b65b4ffa66fee
Source noteuspto-grants-2013_01