Aluminium lithium hydride → HCID 68508294, compound

Participants

Reaction Steps

A solution of methyl 2-(4-methoxy-2,6-dimethylphenylsulfonyl)-1,2,3,4-tetrahydroisoquinoline-7-carboxylate (3.85 mmol, 1 equiv.) in THF (10 ml) was added dropwise to a cold suspension of LAH (7.7 mmol, 2 equiv.) in THF (30 ml), and the resulting mixture was stirred for 1 h. THF/water was added to the reaction mixture, and filtration over Celite was carried out. The filtrate was concentrated and the yellow oil so obtained was used in the following stage without further purification.

Provenance & Evidence