5-Amino-1,3,4-thiadiazole-2-sulfonamide → 7-Difluoromethyl-5-(4-trifluoromethyl-phenyl)-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid (5-sulfamoyl-[1,3,4]thiadiazol-2-yl)-amide
Reaction equation
[F:1][CH:2]([c:3]1[cH:4][c:5](-[c:15]2[cH:16][cH:17][c:18]([C:21]([F:22])([F:23])[F:24])[cH:19][cH:20]2)[n:6][c:7]2[n:8]1[n:9][cH:10][c:11]2[C:12](=[O:13])[OH:14])[F:25].[NH2:26][c:27]1[n:28][n:29][c:30]([S:32](=[O:33])(=[O:34])[NH2:35])[s:31]1>>[F:1][CH:2]([c:3]1[cH:4][c:5](-[c:15]2[cH:16][cH:17][c:18]([C:21]([F:22])([F:23])[F:24])[cH:19][cH:20]2)[n:6][c:7]2[n:8]1[n:9][cH:10][c:11]2[C:12](=[O:14])[NH:26][c:27]1[n:28][n:29][c:30]([S:32](=[O:33])(=[O:34])[NH2:35])[s:31]1)[F:25]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-3b8a8195abf14133ab761ed9bae4691e
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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