HCID 59587921, compound → HCID 44595147, compound

Participants

Reaction Steps

A solution of (3S,4S)-tert-butyl 3-azido-4-(prop-2-ynyloxy)pyrrolidine-1-carboxylate (77 mg, 0.29 mmol) in toluene (5 ml) was heated at 120° C. for 16 hours or until TLC analysis shows completed reaction. The solvent was removed under reduced pressure and the residue was purified by flash chromatography, silica gel, gradient hexane:ethyl acetate (3:1) to neat ethyl acetate, to afford the titled compound (74 mg, 96%) as white solid. M.p. 155-157° C.

Provenance & Evidence