Methanol → Methyl 2-hydroxy-3-nitrobenzoate

Participants

Reaction Conditions

Reaction Steps

20 g (109 mmol) of 2-hydroxy-3-nitrobenzoic acid was dissolved in 150 mL of methanol, 7 mL of strong sulfuric acid was added dropwise thereto. The mixture was stirred under heat-reflux for 24 hr. The mixture was cooled to 0° C., filtered and washed with distilled water, followed by drying under vacuum to obtain the title compound (20 g, yield: 93%)

Provenance & Evidence