HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1809192Generated: October 30, 2026
Bromoacetone → 1,6-Dimethyl-8-oxo-7,8-dihydro-imidazo[1,2-a]pyrazin-1-ium bromide salt
https://huagongshe.com/reaction/1809192
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Bromoacetone | HCID 11715 | — |
| Reactant | 1-methyl-1H-imidazole-2-carboxamide | HCID 447041 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | 1,6-Dimethyl-8-oxo-7,8-dihydro-imidazo[1,2-a]pyrazin-1-ium bromide salt | HCID 86655089 | 123.2% |
Reaction Steps
A mixture of 1-Methyl-1H-imidazole-2-carboxylic acid amide (3.0 g, 14.3 mmol), bromoacetone (2.36 g, 17.2 mmol) and acetonitrile (40 mL) is stirred overnight at 80° C. The solid formed is filtered and washed with acetonitrile to give 1,6-dimethyl-8-oxo-7,8-dihydro-imidazo[1,2-a]pyrazin-1-ium bromide salt (4.3 g, 86%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08362018B2 |
|---|
| Source dataset | uspto-grants-2013_01 |
|---|
| ORD ID | ord-d10cd3f347774ff1a7c89d2309ce0c33 |
|---|
| Source note | uspto-grants-2013_01 |
|---|
