Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Trifluoroacetic acid → HCID 86655088, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Trifluoroacetic acid | HCID 6422 | — |
| 반응물 | 3-Cyanobenzene-1-sulfonamide | HCID 2808718 | — |
| 촉매 | Palladium | HCID 23938 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | HCID 86655088 | HCID 86655088 | — |
반응 단계
TFA (5 mL) can be added to a solution of 3-cyano-benzenesulfonamide (0.90 g, 4.94 mmol) in EtOH (50 mL) followed by Pd/C (100 mg) and the mixture hydrogenated at 40 psi and r.t. for 20 h. The reaction mixture can be filtered through celite and the solvent concentrated to give 3-Aminomethyl-benzenesulfonamide TFA salt as a white solid in quantitative yield.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08362018B2 |
| 출처 데이터셋 | uspto-grants-2013_01 |
| ORD ID | ord-e4e9a0a35d394ab39795a9e29dcf9336 |
| 출처 메모 | uspto-grants-2013_01 |