N-(4-Fluorophenyl)formamide → 2-Chloro-N-(4-fluorophenyl)-9-methyl-9H-purin-6-amine

HRID 1809221Notes

Reaction equation

HRID 1809221 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][C:5]([NH:8][CH:9]=O)=[CH:4][CH:3]=1.[Cl:11][C:12]1[N:20]=[C:19]2[C:15]([N:16]=[CH:17][N:18]2[CH3:21])=C(Cl)[N:13]=1>>[Cl:11][C:12]1[N:20]=[C:19]2[C:15]([N:16]=[CH:17][N:18]2[CH3:21])=[C:9]([NH:8][C:5]2[CH:6]=[CH:7][C:2]([F:1])=[CH:3][CH:4]=2)[N:13]=1

Participants

3

Reactant 2

HCID 237239N-(4-Fluorophenyl)formamideHCID 17125532,6-dichloro-9-methyl-9H-purine

Product 1

HCID 592936292-Chloro-N-(4-fluorophenyl)-9-methyl-9H-purin-6-amine

Procedure

Was prepared according to Example 3 from N-(4-fluoro-phenyl)-formamide and 2,6-dichloro-9-methyl-9H-purine.

Workup

  1. customWas prepared

Sources & evidence

ORD record
ord-4f943904aca545e0881c70fc67bd1418
Source dataset
uspto-grants-2013_01
Patent number
US08362024B2

Reaction notes

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