2-Chloro-N-(4-chlorophenyl)-9-methyl-9H-purin-6-amine → [2-(5-Chloro-3-methyl-pyrazol-1-yl)-9-methyl-9H-purin-6-yl]-(4-chloro-phenyl)-amine
Reaction equation
Cl[C:2]1[N:10]=[C:9]2[C:5]([N:6]=[CH:7][N:8]2[CH3:11])=[C:4]([NH:12][C:13]2[CH:18]=[CH:17][C:16]([Cl:19])=[CH:15][CH:14]=2)[N:3]=1.[Cl:20][C:21]1[NH:25][N:24]=[C:23]([CH3:26])[CH:22]=1>>[Cl:20][C:21]1[N:25]([C:2]2[N:10]=[C:9]3[C:5]([N:6]=[CH:7][N:8]3[CH3:11])=[C:4]([NH:12][C:13]3[CH:18]=[CH:17][C:16]([Cl:19])=[CH:15][CH:14]=3)[N:3]=2)[N:24]=[C:23]([CH3:26])[CH:22]=1Participants
3
Procedure
Was prepared according to Example 6 from (2-chloro-9-methyl-9H-purin-6-yl)-(4-chloro-phenyl)-amine and 5-chloro-3-methyl-1H-pyrazole.
Workup
- customWas prepared
Sources & evidence
- ORD record
- ord-8b3c77be7c4646f7b899f5ed2b1a22b4
- Source dataset
- uspto-grants-2013_01
- Patent number
- US08362024B2
Reaction notes
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