HCID 59255055, compound → HCID 59255064, compound
Reaction equation
[Br:1][C:2]1[CH:3]=[C:4]([C:13]([O:15]CC)=[O:14])[C:5](=[O:12])[N:6]([CH:9]([CH3:11])[CH3:10])[C:7]=1[CH3:8].ClC1C=C(C(OCC)=O)C(=O)N(C(C)C)C=1C>>[Br:1][C:2]1[CH:3]=[C:4]([C:13]([OH:15])=[O:14])[C:5](=[O:12])[N:6]([CH:9]([CH3:11])[CH3:10])[C:7]=1[CH3:8]Participants
3
Procedure
The title compound was prepared according to the procedure of Example 1(7), but using ethyl 5-bromo-1-isopropyl-6-methyl-2-oxo-1,2-dihydropyridine-3-carboxylate as prepared in 4(1) instead of ethyl 5-chloro-1-isopropyl-6-methyl-2-oxo-1,2-dihydropyridine-3-carboxylate.
Sources & evidence
- ORD record
- ord-87d4704ae6394ca3ac734743210a06a5
- Source dataset
- uspto-grants-2013_01
- Patent number
- US08362038B2
Reaction notes
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