Tetrabutylammonium Fluoride → HCID 69809508, compound

Participants

Reaction Steps

TBAF (1.3 eq., 1M in THF) was added dropwise to a solution of (C4) in dry THF (0.1 M) and allowed to stir at RT for 1 h. The reaction mixture was diluted with EtOAc and washed with 1N HCl (2×), sat. aq. NaHCO3, brine and dried (Na2SO4). Evaporation of the solvent yielded (100%) the title compound. 1H NMR (300 MHz, DMSO-d6, 300K) δ 9.33 (1H, s), 8.36 (2H, d, 8.5 Hz), 8.11 (2H, d, J=8.2 Hz*−), 7.62 (1H, d, J=8.5 Hz), 7.36 (1H, t, J=7.3 Hz), 7.12 (1H, d, J=6.6 Hz), 5.36 (1H, bt, J=5.4 Hz), 4.84 (2H, d, J=5.2 Hz). MS (ES+) C15H11N3O required: 249, found: 250 (M+H)+.

Provenance & Evidence