Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 180980Generated: October 25, 2026

Tetrahydrofuran → (3SR,4RS)-3-(3,4-Dichloro-phenyl)-4-[(3-fluoro-4-trifluoromethyl-benzyl)-methyl-amino]-pyrrolidine-1-carboxylic acid 3-chloro-propyl ester

https://huagongshe.com/reaction/180980

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantTriethylamineHCID 8471—
ReactantCarbonochloridic acid, 3-chloropropyl esterHCID 69399—
Reactant[(3RS,4SR)-4-(3,4-Dichloro-phenyl)-pyrrolidin-3-yl]-(3-fluoro-4-trifluoromethyl-benzyl)-methyl-amineHCID 75231672—
Product(3SR,4RS)-3-(3,4-Dichloro-phenyl)-4-[(3-fluoro-4-trifluoromethyl-benzyl)-methyl-amino]-pyrrolidine-1-carboxylic acid 3-chloro-propyl esterHCID 72253477—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (6/10)
ORD IDord-98d0dabd32c24e1fb0ca8e26b991f070
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (6/10)