HuagongsheHuagongshe Chemistry Print Report · For research reference only
7-Methoxy-4-nitro-1-(propan-2-yl)-1H-indole → HCID 59551030, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 7-Methoxy-4-nitro-1-(propan-2-yl)-1H-indole | HCID 53414193 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethylacetate methanol | HCID 21584119 | — |
| Product | HCID 59551030 | HCID 59551030 | — |
Reaction Steps
A solution of 1-isopropyl-7-methoxy-4-nitro-1H-indole (T) (1 eq) and palladium 10% on activated carbon (0.1 wt eq) in methanol/ethyl acetate (1:1) was shaken on a Parr hydrogenation apparatus under hydrogen for 1 hr. The reaction was then filtered through Celite and evaporated to dryness to produce the desired product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08362055B2 |
| Source dataset | uspto-grants-2013_01 |
| ORD ID | ord-f727dc17ff974d0ab83fd7b0926cd9ff |
| Source note | uspto-grants-2013_01 |