Celecoxib → HCID 67236817, compound

Participants

Reaction Steps

To a solution of celecoxib (129.3 mg; 0.3390 mmol) in diethyl ether (5.0 mL) was added a solution of diglyme (0.100 mL; 0.698 mmol) in diethyl ether (3.0 mL). The volatiles were allowed to evaporate slowly yielding a white solid. The solid continued to crystallize as the solvent was reduced (2 mL) and subsequently cooled. The white powder was collected via filtration and air-dried. The solid was found to be a diglyme solvate of celecoxib.

Provenance & Evidence