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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1810006Generated: November 3, 2026

1-(Bromomethyl)-2,4-difluorobenzene → HCID 178460774, compound

https://huagongshe.com/reaction/1810006

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(Bromomethyl)-2,4-difluorobenzeneHCID 90297—
ReactantEthyl 2-[(2-amino-1,3-thiazol-5-yl)sulfanyl]-2-methylpropanoateHCID 57481427—
ReactantHCID 178454946HCID 178454946—
ProductHCID 178460774HCID 178460774—

Reaction Steps

The compound was prepared following an analogous procedure to the one described for the synthesis of 3-{2-[3-[2-(2-chloro-benzyloxy)-ethyl]-3-(trans-4-methyl-cyclohexyl)-ureido]-thiazol-5-ylsulfanyl}-2,2-dimethyl-propionic acid using 1-bromomethyl-2,4-difluoro-benzene and 2-(2-amino-thiazol-5-ylsulfanyl)-2-methyl-propionic acid ethyl ester.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08362049B2
Source datasetuspto-grants-2013_01
ORD IDord-a7320708ac824ab4b8dfa1e147662f27
Source noteuspto-grants-2013_01